Protein Kinase-mediated Decisions Between Life and Death
Paperback Engels 2022 9783030498467Samenvatting
Protein phosphorylation via protein kinases is an inevitable process that alters physiological and pathological functions of the cells. Thus, protein kinases play key roles in the regulation of cell life or death decisions. Protein kinases are frequently a driving factor in a variety of human diseases including aging and cellular senescence, immune system and endothelial dysfunctions, cancers, insulin resistance, cholestasis and neurodegenerative diseases, as well as bacterial resistance in persistent infections. Recent developments in quantitative proteomics provide important opinions on kinase inhibitor selectivity and their modes of action in the biological context. Protein Kinase-mediated Decisions Between Life and Death aims to have the reader catch insights about up-to-date opinions on “Protein Kinases” related pathways that threaten human health and life. As “Protein Kinases” are related to many health problems, clinicians, basic science researchers and students need this information.
Chapter “Signal Transduction in Immune Cells and Protein Kinases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Specificaties
Lezersrecensies
Inhoudsopgave
<p>Corresponding Author</p>
<p>Protein kinase-mediated decision between life and death</p>
<p>Atilla ENGIN</p>
<p>Aging, cellular senescence and protein kinases</p>
<p>Ayse Basak ENGIN</p>
<p>ERK1/2 MAP kinase, its regulation and role in cellular activities including apoptosis and cell survival</p>
<p>Imran ALI</p>
<p>Signal transduction in immune cells and protein kinases</p>
<p>Monica NEAGU</p>
<p>Role of protein kinase C in immune cell activation and its implication chemical-induced immunotoxicity</p>
<p>Emanuela CORSINI</p>
<p>Metabolic stress and immunity</p>
<p>Dietmar FUCHS</p>
<p>Two-component signal transduction systems in antibiotic resistance</p>
<p>Evren Doruk ENGIN</p>
<p>Oxidative stress-related endothelial cell death and protein kinases </p>
<p>Atilla ENGIN</p>
<p>Protein kinase inhibitors in traumatic brain injury and repair </p>
<p>Hari SHARMA</p>
<p>Activation of tropomyosin-related kinase receptor B by N-acetyl-serotonin: implications for neuroprotection</p>
<p>Gregory OXENKRUG</p>
<p>Glucolipotoxicity-related beta cell death and protein kinases </p>
<p>Atilla ENGIN</p>
<p>Amyloid beta toxicity in Alzheimer’s Disease and neuronal death-associated protein kinases</p>
<p>Ayse Basak ENGIN</p>
<p>Protein kinases and cell death in hematological disorders </p>
<p>Ibrahim C. HAZNEDAROGLU</p>
<p>A crosstalk between dual-specific phosphatases and dual-specific protein kinases can be a potential therapeutic target for anti-cancer therapy</p>
<p>Basak CELTIKCI</p>
<p>Bile acid toxicity and protein kinases</p>
<p>Atilla ENGIN</p>
<p>Nanoparticle toxicity: Protein kinases and cell death</p>
<p>Ayse Basak ENGIN</p>
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